STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3A2D1_LATCHIntegrase catalytic domain-containing protein. (347 aa)    
Predicted Functional Partners:
RBBP7
WD_REPEATS_REGION domain-containing protein.
    
 0.830
LOC102347269
Retinoblastoma binding protein 4, like.
    
 0.830
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.830
HDAC3
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.687
HDAC8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.687
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.687
ARID4A
AT-rich interaction domain 4A.
    
 0.675
FANCM
FA complementation group M.
    
 0.639
H3A7C6_LATCH
RT_RNaseH_2 domain-containing protein.
 
 
   0.620
EP300
E1A binding protein p300.
   
  0.582
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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