Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSNK2A2Casein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (347 aa)    
Predicted Functional Partners:
CSNK2B
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.994
DVL3
Dishevelled segment polarity protein 3.
    
 0.964
DVL2
Dishevelled segment polarity protein 2.
    
 0.964
DVL1
Dishevelled segment polarity protein 1.
    
 0.964
FUNDC1
FUN14 domain containing 1.
   
 0.959
H2ZS17_LATCH
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.916
CTNNB1
Catenin beta 1.
    
 0.913
LOC102348027
Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.
  
  
 
0.901
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.876
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.876
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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