STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HNF4GHepatocyte nuclear factor 4 gamma. (332 aa)    
Predicted Functional Partners:
CREBBP
CREB binding protein.
    
 
 0.645
NR0B2
Nuclear receptor subfamily 0 group B member 2.
   
0.635
A1CF
APOBEC1 complementation factor.
   
  
 0.630
PPARGC1A
PPARG coactivator 1 alpha.
    
 
 0.622
GATA5
GATA binding protein 5.
   
 
 0.554
HINFP
Histone H4 transcription factor.
    
 
 0.506
NCOR1
Nuclear receptor corepressor 1.
    
 0.496
NCOR2
Nuclear receptor corepressor 2.
    
 0.496
SLC10A2
Solute carrier family 10 member 2.
      
 0.470
H3AM65_LATCH
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.470
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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