Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHF3Uncharacterized protein. (1992 aa)    
Predicted Functional Partners:
NIPBL
Nipped-B protein.
   
  
 0.964
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
  
 0.868
H3A8J5_LATCH
Uncharacterized protein.
   
 0.817
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.817
BPTF
Bromodomain PHD finger transcription factor.
   
    0.812
ERGIC3
ERGIC and golgi 3.
      
 0.807
RCN3
Reticulocalbin 3, EF-hand calcium binding domain.
      
 0.792
SUPT5H
Transcription elongation factor SPT5.
    
 0.787
POLR2E
RNA polymerase II subunit E.
    
  0.784
RHOV
Ras homolog family member V.
      
 0.745
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]