STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHF3Uncharacterized protein. (1992 aa)    
Predicted Functional Partners:
NIPBL
Nipped-B protein.
   
  
 0.954
POLR2E
RNA polymerase II subunit E.
    
  0.878
H3A8J5_LATCH
Uncharacterized protein.
    
 0.850
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.850
POLR2C
RNA polymerase II subunit C.
    
  0.779
ERGIC3
ERGIC and golgi 3.
      
 0.761
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
  
 0.753
POLR2I
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
 0.753
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.748
RCN3
Reticulocalbin 3, EF-hand calcium binding domain.
      
 0.747
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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