STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THOP1Thimet oligopeptidase 1. (684 aa)    
Predicted Functional Partners:
SYDE2
Synapse defective Rho GTPase homolog 2.
      
 0.570
WDR63
WD repeat domain 63.
      
 0.532
SGTA
Small glutamine rich tetratricopeptide repeat containing alpha.
      
 0.507
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
 
 
  
 0.443
DPP3
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
   
  
 0.438
HSPE1
Heat shock protein family E (Hsp10) member 1; Belongs to the GroES chaperonin family.
  
 
 0.438
FXN
Frataxin.
   
 
 0.437
CIB3
Calcium and integrin binding family member 3.
    
 
 0.432
NEDD9
Neural precursor cell expressed, developmentally down-regulated 9.
   
  
 0.430
LUM
Lumican.
      
 0.426
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.