Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (740 aa)    
Predicted Functional Partners:
ACOX1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.982
ACOX3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.981
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.977
ACAA1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.965
ECI2
Enoyl-CoA delta isomerase 2.
  
 0.843
ERAL1
Era like 12S mitochondrial rRNA chaperone 1.
      
 0.782
AMACR
Alpha-methylacyl-CoA racemase.
  
 
 0.781
HADHB
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.767
TYSND1
Trypsin domain containing 1.
    
 0.754
PEX5
Peroxisomal biogenesis factor 5.
   
 0.745
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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