Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHANK1SH3 and multiple ankyrin repeat domains 1. (1849 aa)    
Predicted Functional Partners:
DLGAP1
DLG associated protein 1.
   
 0.983
HOMER1
Homer scaffold protein 1.
    
 0.973
DLGAP3
DLG associated protein 3.
   
 0.942
DLGAP2
DLG associated protein 2.
   
 0.933
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
 0.877
DLGAP4
DLG associated protein 4.
   
 0.874
H2ZSE1_LATCH
Uncharacterized protein.
   
 0.833
HOMER3
Homer scaffold protein 3b.
    
 0.815
ANKS1B
Ankyrin repeat and sterile alpha motif domain containing 1B.
   
 0.814
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.700
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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