STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHANK1SH3 and multiple ankyrin repeat domains 1. (1849 aa)    
Predicted Functional Partners:
DLGAP1
DLG associated protein 1.
   
 0.870
DLGAP3
DLG associated protein 3.
   
 0.844
DLGAP2
DLG associated protein 2.
   
 0.812
DLGAP4
DLG associated protein 4.
    
 0.805
HOMER1
Homer scaffold protein 1.
    
 0.784
H2ZSE1_LATCH
Uncharacterized protein.
    
 0.760
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.732
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 0.701
LOC102349972
Uncharacterized protein.
   
 0.645
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.645
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.