Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SYNGAP1Synaptic Ras GTPase activating protein 1. (1257 aa)    
Predicted Functional Partners:
RASA1
RAS p21 protein activator 1.
     
 0.584
ARHGAP5
Rho GTPase activating protein 5.
   
 0.581
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
 
 0.568
DLGAP3
DLG associated protein 3.
   
 
 0.536
NF1
Neurofibromin 1.
   
 0.532
RND3
Rho family GTPase 3.
    
 0.531
ARHGAP35
Rho GTPase activating protein 35b.
   
 0.530
HOMER1
Homer scaffold protein 1.
    
 
 0.526
RASA2
RAS p21 protein activator 2.
   
 0.512
LOC102357287
Rho-GAP domain-containing protein.
   
 0.512
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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