Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A2S0_LATCHIg-like domain-containing protein; Belongs to the MHC class I family. (354 aa)    
Predicted Functional Partners:
LOC106706091
Uncharacterized protein.
   
 
  0.678
PDIA3
Protein disulfide-isomerase.
   
 
  0.678
CALR3
Calreticulin.
   
 
  0.671
H3AVH0_LATCH
Uncharacterized protein.
    
  0.658
H3AJ79_LATCH
Ig-like domain-containing protein.
     
  0.651
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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