STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP76Centrosomal protein 76. (638 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
    
 0.904
PLK4
Polo like kinase 4.
    
 0.749
LARGE2
LARGE xylosyl- and glucuronyltransferase 2.
      
 0.699
TMED6
Transmembrane p24 trafficking protein 6.
      
 0.694
CCP110
Centriolar coiled-coil protein 110.
    
 
 0.692
CEP290
Centrosomal protein 290.
    
 
 0.647
LOC102348724
C2 domain-containing protein.
     
 0.634
PLK3
Polo like kinase 3.
    
 0.632
PLK5
Serine/threonine-protein kinase PLK.
    
 0.632
PLK2
Serine/threonine-protein kinase PLK.
    
 0.632
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.