Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MSH3MutS homolog 3; Component of the post-replicative DNA mismatch repair system (MMR). (798 aa)    
Predicted Functional Partners:
MLH1
MutL homolog 1.
 
 0.998
PMS2
PMS1 homolog 2, mismatch repair system component.
 
 0.991
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.990
LOC102360187
MutS homolog 2 (E. coli).
  
0.989
PMS1
PMS1 homolog 1, mismatch repair system component.
 
 0.988
H2ZX83_LATCH
MutS homolog 2 (E. coli).
   
 0.987
SNX8
Sorting nexin 8.
    
   0.963
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 
0.957
EXO1
Exonuclease 1.
   
 0.917
MLH3
MutL homolog 3.
  
 0.915
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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