STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MSS51MSS51 mitochondrial translational activator. (353 aa)    
Predicted Functional Partners:
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
      
 0.668
H4C11
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.652
H3B976_LATCH
Uncharacterized protein.
      
 0.604
EED
Embryonic ectoderm development.
    
 0.595
ARHGEF10
Rho guanine nucleotide exchange factor 10.
   
  
 0.587
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
    
 0.571
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase.
   
 
 0.567
IGSF22
Immunoglobulin superfamily member 22.
   
 
 0.566
MPHOSPH8
M-phase phosphoprotein 8.
    
 0.563
MCU
Mitochondrial calcium uniporter.
    
 
 0.563
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.