STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL11ABAF chromatin remodeling complex subunit BCL11A. (798 aa)    
Predicted Functional Partners:
GATA1
GATA binding protein 1b.
    
 0.618
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
   
  
 0.597
RNF220
Ring finger protein 220.
      
 0.590
SS18L1
SS18L1 subunit of BAF chromatin remodeling complex.
    
 
 0.575
BCL7C
Uncharacterized protein.
      
 0.571
RBBP7
WD_REPEATS_REGION domain-containing protein.
    
 0.539
LOC102347269
Retinoblastoma binding protein 4, like.
    
 0.539
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.539
LMO2
LIM domain only 2.
    
 
 0.526
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.508
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.