Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
USPL1Ubiquitin specific peptidase like 1. (1163 aa)    
Predicted Functional Partners:
DESI1
Desumoylating isopeptidase 1.
      
 0.797
C19orf54
Chromosome 19 open reading frame 54.
    
 
 0.796
USP22
Ubiquitin carboxyl-terminal hydrolase.
    
 0.792
RANGAP1
Ran GTPase activating protein 1.
    
 0.750
SUMO3
Small ubiquitin-related modifier.
    
 0.715
LOC102363126
Small ubiquitin-related modifier.
    
 0.715
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.712
ICE2
Interactor of little elongation complex ELL subunit 2.
   
 
 0.702
SENP6
SUMO specific peptidase 6.
    
 
 0.692
INTS14
Integrator complex subunit 14.
    
 0.689
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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