Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSTSomatostatin. (118 aa)    
Predicted Functional Partners:
SSTR3
Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family.
   
 0.990
H3ABM6_LATCH
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
 0.988
SSTR1
Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.987
LOC102349660
Somatostatin receptor 1b; Belongs to the G-protein coupled receptor 1 family.
   
 0.983
SSTR4
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
 0.983
SSTR2
Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 0.983
LOC102356917
Cortistatin.
   
 
 0.976
PVALB
Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).
      
 0.946
APP
Amyloid beta precursor protein.
   
 
 0.935
NPY
Neuropeptide Y.
   
 
 0.908
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (8%) [HD]