Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BTCEGF-like domain-containing protein. (177 aa)    
Predicted Functional Partners:
ERBB4-2
Protein kinase domain-containing protein.
    
 0.959
AREG
Amphiregulin.
     
 0.950
HBEGF
Heparin binding EGF like growth factor.
     
 0.812
EPGN
Epithelial mitogen.
     
 0.799
ERBB3
Protein kinase domain-containing protein.
    
 0.710
KIF24
Kinesin family member 24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.671
ENOX1
Ecto-NOX disulfide-thiol exchanger 1.
      
 0.668
ERBB4
Protein kinase domain-containing protein.
    
 0.618
H3A7N7_LATCH
GF_recep_IV domain-containing protein.
    
 0.618
ERBB2
Receptor protein-tyrosine kinase.
    
 0.618
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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