Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB41Zinc finger and BTB domain containing 41. (915 aa)    
Predicted Functional Partners:
PTAR1
Protein prenyltransferase alpha subunit repeat containing 1.
      
 0.615
MYSM1
Myb like, SWIRM and MPN domains 1.
   
  0.560
SOCS6
Suppressor of cytokine signaling 6.
     
 0.519
PCGF5
Polycomb group ring finger 5.
   
 0.519
NTHL1
Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
      
 0.510
XIAP
X-linked inhibitor of apoptosis.
   
 
 0.498
AHSG
Alpha 2-HS glycoprotein.
    
 0.492
RECQL
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
     
 0.481
SHC2
SHC (Src homology 2 domain containing) transforming protein 2.
    
 
 0.478
SNX16
Sorting nexin 16.
      
 0.476
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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