STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC2Arrestin domain containing 2. (407 aa)    
Predicted Functional Partners:
LOC102347712
Thioredoxin; Belongs to the thioredoxin family.
    
 0.778
SSPN
Sarcospan.
   
  
 0.721
M3XI97_LATCH
Thioredoxin domain-containing protein.
    
 0.688
PLXNB1
Plexin B1.
      
 0.662
LOC102354290
Uncharacterized protein.
    
 0.650
SEMA4D
Semaphorin 4D; Belongs to the semaphorin family.
      
 0.642
YES1
Tyrosine-protein kinase.
    
 
 0.588
NEDD4L
E3 ubiquitin-protein ligase.
    
 
 0.480
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.480
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2.
    
 
 0.480
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.