Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC2Arrestin domain containing 2. (407 aa)    
Predicted Functional Partners:
WSCD2
WSC domain containing 2.
      
 0.800
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.787
PPM1F
Protein phosphatase, Mg2+/Mn2+ dependent 1F.
    
 
 0.783
LOC102347712
Thioredoxin; Belongs to the thioredoxin family.
    
 0.734
SSPN
Sarcospan.
   
  
 0.733
GSC2
Goosecoid homeobox 2.
      
 0.707
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.679
RASSF1
Ras association domain family member 1.
      
 0.671
LOC102357064
DiGeorge syndrome critical region gene 6.
      
 0.662
YES1
Tyrosine-protein kinase.
    
 
 0.662
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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