Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC102361022S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (391 aa)    
Predicted Functional Partners:
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
  
 0.996
MTR
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.971
LOC102351553
Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism.
  
 
 0.971
LOC102347529
Zgc:172121.
  
 
 0.968
AMD1
S-adenosylmethionine decarboxylase proenzyme.
   
 
 0.953
GNMT
Glycine N-methyltransferase.
   
 
 0.941
H3A2C6_LATCH
Amine oxidase.
     
 0.913
LOC102367420
Amine oxidase.
    
 0.912
LOC102355982
Amine oxidase.
    
 0.912
DNMT3A
DNA methyltransferase 3 alpha.
     
 0.905
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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