STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDH8Uncharacterized protein. (976 aa)    
Predicted Functional Partners:
EGFL6
EGF like domain multiple 6.
   
 0.668
ANKS3
Ankyrin repeat and sterile alpha motif domain containing 3.
    
 0.599
WDR90
WD repeat domain 90.
     
 0.595
RHOT2
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
    
 0.591
COG3
Component of oligomeric golgi complex 3.
      
 0.589
WDR24
WD repeat domain 24.
      
 0.589
RHBDL1
Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
  
 0.587
ARHGAP6
Rho GTPase activating protein 6.
      
 0.579
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
     
 0.577
AMOTL1
Angiomotin like 1.
     
 0.573
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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