Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PCDH8Uncharacterized protein. (976 aa)    
Predicted Functional Partners:
RHOT2
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
     
 0.668
WDR90
WD repeat domain 90.
     
 0.666
ANKS3
Ankyrin repeat and sterile alpha motif domain containing 3.
    
 0.665
RHBDL1
Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
  
 0.659
ARHGAP6
Rho GTPase activating protein 6.
      
 0.659
WDR24
WD repeat domain 24.
      
 0.659
COG3
Component of oligomeric golgi complex 3.
      
 0.656
HIVEP1
Human immunodeficiency virus type I enhancer binding protein 1.
     
 0.654
EGFL6
EGF like domain multiple 6.
    
 0.542
GCGR
Glucagon receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.497
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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