Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC174Coiled-coil domain containing 174. (449 aa)    
Predicted Functional Partners:
EIF4A3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 
 0.948
ZNF706
Zgc:91910.
      
 0.921
NRDE2
NRDE-2, necessary for RNA interference, domain containing.
    
 
 0.887
TATDN2
Uncharacterized protein.
 
 
  
 0.887
H3B976_LATCH
Uncharacterized protein.
   
  
 0.864
GPATCH1
G-patch domain containing 1.
    
 
 0.715
GPR22
G protein-coupled receptor 22.
      
 0.713
CRBN
Cereblon.
      
 0.707
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
    
   0.650
MTREX
Mtr4 exosome RNA helicase.
    
 
 0.642
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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