Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKDD1BAnkyrin repeat and death domain containing 1B. (501 aa)    
Predicted Functional Partners:
CDH24
Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.793
TMEM30B
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
    
 
 0.679
MOB3C
MOB kinase activator 3C.
      
 0.626
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
 0.582
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.569
TPTE2
Transmembrane phosphatase with tensin homology.
   
 0.569
NRCAM
Neuronal cell adhesion molecule.
    
 0.562
CHL1
Cell adhesion molecule L1 like.
    
 0.562
L1CAM
L1 cell adhesion molecule.
    
 0.562
NFASC
Neurofascin.
    
 0.562
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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