Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TMX4Thioredoxin related transmembrane protein 4. (293 aa)    
Predicted Functional Partners:
ZDHHC6
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.927
TMEM161A
Transmembrane protein 161A.
      
 0.846
TMX2
Thioredoxin-related transmembrane protein 2a.
    
 
 0.821
GPCPD1
Glycerophosphocholine phosphodiesterase 1.
   
  
 0.796
LOC102357927
VKc domain-containing protein.
      
 0.795
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.777
HSD11B1
Hydroxysteroid 11-beta dehydrogenase 1.
    
 
 0.727
CLGN
Calmegin.
   
 0.698
CANX
Calnexin.
   
 0.698
TMEM214
Transmembrane protein 214.
      
 0.691
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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