STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3A3F5_LATCHSERPIN domain-containing protein; Belongs to the serpin family. (325 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.793
LOC102360396
Si:dkey-26g8.5; Belongs to the peptidase C1 family.
   
 0.615
VTN
Vitronectin b.
   
 0.535
FGA
Fibrinogen alpha chain.
   
 0.507
LOC102365039
Cathepsin S; Belongs to the peptidase C1 family.
    
 0.505
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
    
 0.505
FGB
Fibrinogen beta chain.
   
 0.447
LOC102351388
Cathepsin L.1; Belongs to the peptidase C1 family.
    
 0.440
LOC102358409
Uncharacterized protein.
   
 0.440
FGG
Fibrinogen gamma chain.
   
 0.439
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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