STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN3Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (871 aa)    
Predicted Functional Partners:
H3B8L2_LATCH
Protein kinase domain-containing protein.
    
 0.941
GRB2
Growth factor receptor bound protein 2.
   
 0.729
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
  0.629
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
  0.629
STAM2
Signal transducing adaptor molecule 2.
    
 0.606
STAM
Signal transducing adaptor molecule.
    
 0.606
H3B7E6_LATCH
Uncharacterized protein.
    
 0.602
HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 0.602
MAPK13
Mitogen-activated protein kinase.
    
 0.596
MAPK14
Mitogen-activated protein kinase.
    
 0.596
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.