Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LIPELipase E, hormone sensitive type. (734 aa)    
Predicted Functional Partners:
LOC102362951
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
 0.968
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.968
PRKAR2B
Protein kinase cAMP-dependent type II regulatory subunit beta.
     
 0.902
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta.
     
 0.902
PRKAR1A
Protein kinase cAMP-dependent type I regulatory subunit alpha.
     
 0.902
PRKAR2A
Protein kinase cAMP-dependent type II regulatory subunit alpha.
     
 0.902
PNPLA2
Patatin like phospholipase domain containing 2.
   
 
 0.822
MGLL
Monoglyceride lipase.
     
 0.805
BCL3
BCL3 transcription coactivator.
    
 
 0.794
H2ZT99_LATCH
Perilipin; Belongs to the perilipin family.
   
 0.791
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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