Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102353186Hes family bHLH transcription factor 6. (236 aa)    
Predicted Functional Partners:
HES1
Hes family bHLH transcription factor 1.
    
 
 0.730
HES4
Hes family bHLH transcription factor 4.
    
 
 0.730
ASCL1
Achaete-scute family bHLH transcription factor 1.
    
 0.621
NMNAT3
Nicotinamide-nucleotide adenylyltransferase.
      
 0.619
MSC
Musculin.
    
 0.602
LOC102354037
Hairy-related 8.2.
    
 
 0.588
NEUROG2
Neurogenin 2.
    
 0.540
NEUROG3
Neurogenin 3.
    
 0.540
NEUROG1
Neurogenin 1.
    
 0.540
CLSTN2
Uncharacterized protein.
      
 0.526
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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