Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C1RComplement C1r; Belongs to the peptidase S1 family. (685 aa)    
Predicted Functional Partners:
C1S
Complement C1s; Belongs to the peptidase S1 family.
  
0.999
H3A3Z8_LATCH
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.978
C1QB
Complement C1q B chain.
   
 0.917
FCN3
Fibrinogen C-terminal domain-containing protein.
   
 0.770
DCN
Decorin; May affect the rate of fibrils formation.
   
 0.756
SERPINF2
Serpin family F member 2; Belongs to the serpin family.
   
 0.706
COLEC10
Collectin subfamily member 10.
    
 0.703
COLEC11
Collectin subfamily member 11.
    
 0.701
JCHAIN
Joining chain of multimeric IgA and IgM.
   
 
 0.650
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
    
 0.649
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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