Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARD3BUncharacterized protein. (1094 aa)    
Predicted Functional Partners:
PRKCZ
Protein kinase C; Belongs to the protein kinase superfamily.
    
 0.876
PRKCI
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.876
LLGL1
LLGL scribble cell polarity complex component 1.
    
 
 0.786
H3ACT9_LATCH
PDZ domain-containing protein.
   
 0.785
H3AHQ4_LATCH
PB1 domain-containing protein.
   
 0.785
PARD6B
Par-6 family cell polarity regulator beta.
   
 0.785
PARD6A
Par-6 family cell polarity regulator alpha.
   
 0.785
ANKLE2
Ankyrin repeat and LEM domain containing 2.
    
 
 0.750
SLTM
SAFB like transcription modulator.
    
 
 0.743
INSC
INSC spindle orientation adaptor protein.
    
 
 0.724
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (44%) [HD]