USP7 protein (Latimeria chalumnae) - STRING interaction network

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Score

USP7

Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1101 aa)

Predicted Functional Partners:

UVSSA

0.993

MDM2

0.985

TP53

0.984

RPS27A

0.980

DAXX

0.972

GMPS

0.965

FOXO4

0.964

FOXO1

0.964

DNMT1

0.964

FOXO6-2

0.964

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAXX	DNMT1	ENSLACP00000001216	ENSLACP00000012502	Death-domain associated protein.	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.648
DAXX	MDM2	ENSLACP00000001216	ENSLACP00000011599	Death-domain associated protein.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.954
DAXX	RPS27A	ENSLACP00000001216	ENSLACP00000008678	Death-domain associated protein.	Ribosomal protein S27a.	0.576
DAXX	TP53	ENSLACP00000001216	ENSLACP00000015915	Death-domain associated protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.937
DAXX	USP7	ENSLACP00000001216	ENSLACP00000004236	Death-domain associated protein.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.972
DNMT1	DAXX	ENSLACP00000012502	ENSLACP00000001216	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Death-domain associated protein.	0.648
DNMT1	RPS27A	ENSLACP00000012502	ENSLACP00000008678	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Ribosomal protein S27a.	0.869
DNMT1	TP53	ENSLACP00000012502	ENSLACP00000015915	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.769
DNMT1	USP7	ENSLACP00000012502	ENSLACP00000004236	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.964
FOXO1	FOXO4	ENSLACP00000011598	ENSLACP00000010904	Forkhead box O1.	Forkhead box O4.	0.547
FOXO1	MDM2	ENSLACP00000011598	ENSLACP00000011599	Forkhead box O1.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.682
FOXO1	TP53	ENSLACP00000011598	ENSLACP00000015915	Forkhead box O1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.645
FOXO1	USP7	ENSLACP00000011598	ENSLACP00000004236	Forkhead box O1.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.964
FOXO4	FOXO1	ENSLACP00000010904	ENSLACP00000011598	Forkhead box O4.	Forkhead box O1.	0.547
FOXO4	MDM2	ENSLACP00000010904	ENSLACP00000011599	Forkhead box O4.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.604
FOXO4	TP53	ENSLACP00000010904	ENSLACP00000015915	Forkhead box O4.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.820
FOXO4	USP7	ENSLACP00000010904	ENSLACP00000004236	Forkhead box O4.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.964
FOXO6-2	MDM2	ENSLACP00000016982	ENSLACP00000011599	Fork-head domain-containing protein.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.494
FOXO6-2	TP53	ENSLACP00000016982	ENSLACP00000015915	Fork-head domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.483
FOXO6-2	USP7	ENSLACP00000016982	ENSLACP00000004236	Fork-head domain-containing protein.	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.	0.964