Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLCH1Phosphoinositide phospholipase C. (1715 aa)    
Predicted Functional Partners:
IPMK
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.912
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
     
 0.900
MINPP1
Multiple inositol-polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family.
     
  0.900
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
   
 0.754
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
   
 0.752
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
    
 0.749
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
 0.749
PIP5KL1
Phosphatidylinositol-4-phosphate 5-kinase like 1.
    
 0.749
MMEL1
Membrane metalloendopeptidase like 1.
      
 0.716
MME
Membrane metalloendopeptidase.
      
 0.715
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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