STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (167 aa)    
Predicted Functional Partners:
H3AHJ4_LATCH
Ion_trans domain-containing protein; Belongs to the potassium channel family.
    
 0.681
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
    
 0.681
TULP4
TUB like protein 4.
      
 0.642
KCNE3
Uncharacterized protein.
      
 0.624
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
     
 0.617
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
      
 0.589
CACNA1G
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
      
 0.573
TRPM4
Transient receptor potential cation channel subfamily M member 4.
      
 0.572
KCNH7
Potassium voltage-gated channel subfamily H member 7.
     
 0.471
KCNH2
Cyclic nucleotide-binding domain-containing protein.
     
 0.471
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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