Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSC22D1Uncharacterized protein. (143 aa)    
Predicted Functional Partners:
TSC22D1-2
Uncharacterized protein.
 
      0.900
TSC22D2
TSC22 domain family member 2.
   
 
 0.724
DDOST
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
      
 0.697
NRBP1
Nuclear receptor binding protein 1.
    
 
 0.660
RPLP2
Ribosomal protein, large P2; Belongs to the eukaryotic ribosomal protein P1/P2 family.
      
 0.654
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.622
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.622
WWP1
E3 ubiquitin-protein ligase.
    
 0.592
AHCY
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
      
 0.564
PSMA7
Proteasome subunit alpha type.
    
 
 0.562
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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