STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3A3T1_LATCHUncharacterized protein. (380 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
    
 0.877
RBBP7
WD_REPEATS_REGION domain-containing protein.
    
 0.652
LOC102347269
Retinoblastoma binding protein 4, like.
    
 0.652
RBBP4
RB binding protein 4, chromatin remodeling factor.
    
 0.652
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.562
H2AZ2
Histone H2A; Belongs to the histone H2A family.
    
 0.547
EP300
E1A binding protein p300.
    
 0.541
LOC102352539
Uncharacterized protein.
    
 0.541
CREBBP
CREB binding protein.
    
 0.541
LOC102350907
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.527
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.