Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SACSSacsin molecular chaperone. (4576 aa)    
Predicted Functional Partners:
NWD2
NACHT and WD repeat domain containing 2.
   
 0.848
APAF1
Apoptotic peptidase activating factor 1.
   
 0.758
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 0.744
DNAJC16
DnaJ heat shock protein family (Hsp40) member C16.
    
 
 0.696
DNAJC28
DnaJ heat shock protein family (Hsp40) member C28.
      
 0.693
C8orf37
Chromosome 8 open reading frame 37.
      
 0.692
RNF216
Ring finger protein 216.
    
 0.686
NFX1
Nuclear transcription factor, X-box binding 1.
      
 0.685
INCENP
INCENP_ARK-bind domain-containing protein.
   
 0.672
PXMP2
Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.659
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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