Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RDH8Retinol dehydrogenase 8a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)    
Predicted Functional Partners:
CYP27C1
Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family.
   
 
 0.923
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.921
BCO1
Beta-carotene oxygenase 1.
   
 
 0.916
H3AY50_LATCH
Retinol saturase (all-trans-retinol 13,14-reductase).
  
 
 0.907
LOC102360472
Si:ch1073-13h15.3.
  
 
 0.907
H3A831_LATCH
Aldehyde oxidase 5.
   
 
 0.901
AOX1
FAD-binding PCMH-type domain-containing protein.
   
 
 0.901
DGAT1
O-acyltransferase.
   
 
 0.900
PNPLA4
PNPLA domain-containing protein.
     
  0.900
LOC102358735
O-acyltransferase.
   
 
 0.900
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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