Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POLDIP2DNA polymerase delta interacting protein 2. (369 aa)    
Predicted Functional Partners:
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 
 0.632
PRIMPOL
Primase and DNA directed polymerase.
      
 0.600
LAD1
Ladinin.
    
   0.560
NOX4
NADPH oxidase 4.
      
 0.552
NOXO1
Uncharacterized protein.
      
 0.517
H3A2Y1_LATCH
Uncharacterized protein.
      
 0.517
CLPP
ATP-dependent Clp protease proteolytic subunit.
   
 
 0.496
CYBA
Cytochrome b-245 alpha chain.
      
 0.469
NCF2
Neutrophil cytosolic factor 2.
      
 0.467
NOXA1
NADPH oxidase activator 1.
      
 0.467
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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