Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MBD5Methyl-CpG binding domain protein 5. (1740 aa)    
Predicted Functional Partners:
ASXL2
ASXL transcriptional regulator 2.
   
 0.981
BAP1
BRCA1 associated protein 1.
    
 0.938
MBD6
MBD domain-containing protein.
  
 
 
0.919
KDM1B
Lysine demethylase 1B.
   
 0.847
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.712
HCFC2
Host cell factor C2.
    
 0.701
HCFC1
Host cell factor C1.
    
 0.701
FOXK1
Forkhead box K1.
    
 0.696
FOXK2
Forkhead box K2.
    
 0.696
LYPD6B
LY6/PLAUR domain containing 6B.
    
 0.664
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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