Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SREK1IP1SREK1 interacting protein 1. (185 aa)    
Predicted Functional Partners:
NUP153
Nucleoporin 153.
    
   0.719
NKAPD1
Zgc:162339.
    
   0.658
CREG2
Cellular repressor of E1A stimulated genes 2.
      
 0.641
H2ZSF9_LATCH
Uncharacterized protein.
      
 0.636
SH3TC2
SH3 domain and tetratricopeptide repeats 2.
      
 0.599
PLEKHF2
Pleckstrin homology and FYVE domain containing 2.
    
   0.588
DIS3L2
DIS3 like 3'-5' exoribonuclease 2.
      
 0.587
LEMD3
LEM domain containing 3.
      
 0.573
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.541
RRP15
Ribosomal RNA processing 15 homolog.
      
 0.500
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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