STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL4DADP ribosylation factor like GTPase 4D. (200 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.844
H3AJ45_LATCH
Uncharacterized protein.
    
 0.734
ITSN1
Intersectin 1 (SH3 domain protein).
    
 0.734
GAK
J domain-containing protein.
    
 0.732
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 0.655
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
   
 0.635
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
    
 0.598
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.594
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
    
 0.548
TRIO
Trio Rho guanine nucleotide exchange factor.
   
 0.544
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.