Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CNNM2Cyclin and CBS domain divalent metal cation transport mediator 2. (789 aa)    
Predicted Functional Partners:
SLC26A1
Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
   
 
 0.693
SLC41A1
Solute carrier family 41 member 1.
      
 0.662
TRPM6
Transient receptor potential cation channel subfamily M member 6.
    
 
 0.634
GMPS
Guanine monophosphate synthase.
    
 0.578
PTP4A2
Protein tyrosine phosphatase 4A2.
    
 
 0.549
SLC13A1
Solute carrier family 13 member 1.
      
 0.549
PTP4A1
Protein tyrosine phosphatase 4A1.
    
 
 0.549
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.518
TMEM241
Transmembrane protein 241.
   
  
 0.507
TRPM7
Transient receptor potential cation channel subfamily M member 7.
    
 
 0.474
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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