Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPAS1PAS domain-containing protein. (743 aa)    
Predicted Functional Partners:
H2ZV55_LATCH
BHLH domain-containing protein.
 
      0.899
EGLN1
Fe2OG dioxygenase domain-containing protein.
    
 0.855
NCOA1
Nuclear receptor coactivator.
    
 0.822
CUL2
Cullin 2; Belongs to the cullin family.
    
 0.790
UBXN7
UBX domain-containing protein 7.
    
  0.742
LOC102364581
Von Hippel-Lindau tumor suppressor.
    
 0.728
NCOA3
Nuclear receptor coactivator.
    
 0.682
NR1I2
Nuclear receptor subfamily 1 group I member 2.
   
 0.681
NR1I3
Nuclear receptor subfamily 1 group I member 3.
   
 0.680
ARNT2
Uncharacterized protein.
    
 0.677
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.