Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IFNGR1Uncharacterized protein. (485 aa)    
Predicted Functional Partners:
JAK1
Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.974
IFNAR1
Uncharacterized protein.
   
0.967
JAK2
Tyrosine-protein kinase.
    
 0.961
LOC102362749
Interfer-bind domain-containing protein.
   
 0.908
LOC102356003
SH2 domain-containing protein.
    
 0.761
LOC102346978
WBP2 N-terminal like.
   
 0.749
WBP2
WW domain binding protein 2.
   
 0.749
STAT1
Signal transducer and activator of transcription.
    
 0.709
STAT2
Signal transducer and activator of transcription.
    
 0.709
TIMM22
Translocase of inner mitochondrial membrane 22.
      
 0.676
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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