Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A478_LATCHPDZ domain-containing protein. (297 aa)    
Predicted Functional Partners:
H3AIG1_LATCH
Uncharacterized protein.
 
   
  0.951
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.902
ESPN
Espin.
    
 0.847
MPP1
Membrane palmitoylated protein 1; Belongs to the MAGUK family.
    
 0.846
GPR176
G protein-coupled receptor 176.
    
 
 0.838
ESPNL
Espin like.
    
 0.797
USH1C
USH1 protein network component harmonin.
     
0.751
IFT88
Intraflagellar transport 88.
    
 0.745
PDZD7
PDZ domain containing 7.
     
0.710
H3A1B7_LATCH
Uncharacterized protein.
    
 0.697
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.