Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC102366786Alkaline phosphatase. (511 aa)    
Predicted Functional Partners:
ACP1
LMWPc domain-containing protein.
    
 0.914
ALPL
Alkaline phosphatase.
  
  
 
0.902
LOC102354239
Alkaline phosphatase.
  
  
 
0.901
TPK1
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
  0.900
LOC102359447
GTP cyclohydrolase 2.
     
  0.900
NTPCR
Nucleoside-triphosphatase, cancer-related.
     
  0.900
GCH1
GTP cyclohydrolase 1.
     
  0.900
PTS
6-pyruvoyltetrahydropterin synthase.
     
  0.900
COX1
Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
      
 0.701
TRIP11
Thyroid hormone receptor interactor 11.
   
 0.589
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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