Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LYSTLysosomal trafficking regulator. (3705 aa)    
Predicted Functional Partners:
PLS1
Plastin 1.
   
 
 0.836
NOLC1
Nucleolar and coiled-body phosphoprotein 1.
      
 0.815
H3B4Z7_LATCH
Uncharacterized protein; Belongs to the cullin family.
      
 0.796
SQSTM1
Sequestosome 1.
   
 
 0.746
NPLOC4
NPL4 homolog, ubiquitin recognition factor.
      
 0.730
FIG4
FIG4 phosphoinositide 5-phosphatase.
   
  
 0.703
RNF6
Ring finger protein 6.
      
 0.703
CLVS2
Clavesin 2.
      
 0.689
MKLN1
Muskelin 1.
   
  
 0.685
ARID5B
AT-rich interaction domain 5B.
      
 0.681
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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