Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MSX1Msh homeobox 1. (256 aa)    
Predicted Functional Partners:
PAX9
Paired box 9.
    
 
 0.940
MSX2
Msh homeobox 2.
   
 
 0.854
BMP4
Bone morphogenetic protein 4.
    
 0.786
FGF4
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.755
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.749
LOC102350471
MAGE domain-containing protein.
    
 
 0.711
BMP7
Bone morphogenetic protein 7.
     
 0.697
GLI1
GLI family zinc finger 1.
    
 
 0.683
TFAP2C
Transcription factor AP-2 gamma.
    
 0.681
TBP
TATA-box binding protein.
    
   0.669
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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