Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRIP2Glutamate receptor interacting protein 2. (1064 aa)    
Predicted Functional Partners:
PICK1
Protein interacting with PRKCA 1.
    
 0.854
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.822
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
    
 0.815
RSPO4
R-spondin 4.
      
 0.732
JPT2
Uncharacterized protein.
      
 0.727
SRCAP
Uncharacterized protein.
   
 
 0.727
GRIPAP1
GRIP1 associated protein 1.
    
 
 0.665
WNT4
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.664
H3ALP0_LATCH
Uncharacterized protein.
      
 0.641
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
   
 0.629
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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