STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UHRF2Uncharacterized protein. (541 aa)    
Predicted Functional Partners:
DNMT1
DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
 0.926
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
    
 
 0.818
H3ALV1_LATCH
Uncharacterized protein.
   
 
 0.739
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
   0.708
USP40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
    
 
 0.521
CDCA8
Nbl1_Borealin_N domain-containing protein.
   
  
 0.448
TMEM183A
Transmembrane protein 183A.
     
 0.441
EHMT2
Euchromatic histone lysine methyltransferase 2.
    
 
 0.440
EHMT1
Euchromatic histone lysine methyltransferase 1.
    
 
 0.440
DTL
Denticleless E3 ubiquitin protein ligase homolog.
   
  
 0.437
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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