Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1076 aa)    
Predicted Functional Partners:
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.747
PLXNA1
Plexin A1.
    
 0.670
TMEM38B
Transmembrane protein 38B.
      
 0.615
H3AY29_LATCH
Uncharacterized protein.
 
    
 0.571
SAP18
Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins.
      
 0.565
PLXNA2
Plexin A2.
    
 0.562
PLXND1
Plexin D1.
    
 0.561
H3A2E1_LATCH
Plexin_cytopl domain-containing protein.
    
 0.539
SLC25A42
Solute carrier family 25 member 42; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.505
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.488
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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